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Isoleucin is an essential amino acid, which is very important for building muscle. About a third of the muscle is composed of isoleucine. The special form 4-hydroxy-isoleucine is also responsible for insulin- and testosterone-budget is an important factor. It modulates the insulin budget. This is especially important for diabetics. But even for the health of non-diabetics, the substance is beneficial. A well-functioning insulin activity acts to regulate testosterone levels.